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Symbol
Name
ID
Irs1
insulin receptor substrate 1
MGI:99454
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Diabetes mellitus
Type II diabetes mellitus
Disease(s) Associated with IRS1
coronary artery disease
type 2 diabetes mellitus

Mouse Phenotypes
abnormal pancreatic beta cell morphology
decreased insulin secretion
Availability Mouse Genotype
Irs1tm1Tka/Irs1tm1Tka
Irs1tm2.1Mfw/Irs1tm2.1Mfw
Irs1tm2.1Mfw/Irs1+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory